Benfuresate

Benfuresate

SCHEMBL54959

CCS(=O)(=O)Oc1ccc2c(c1)C(C)(C)CO2

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
NOTUM Q6P988 2/20 0.40
RARB P10826 3/20 0.39
RARG P13631 3/20 0.39
RARA P10276 2/20 0.39
ALPI P09923 2/20 0.38
ALPL P05186 1/20 0.38
CA2 P00918 2/20 0.37
RXRA P19793 1/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP14 P50281 2/20 0.36
MMP7 P09237 1/20 0.36
HTR1A P08908 1/20 0.36
HTR2B P41595 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ACACB O00763 1/20 0.35
CA12 O43570 1/20 0.35
ENPP3 O14638 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benfuresate SCHEMBL29396663 1.00 PTGS1 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL4890261 1.00 PTGS1 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL7520848 0.96 PTGS1 (0.39) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11449645 0.91 CA12 (0.41) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11449273 0.89 PTGS1 (0.39) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11448349 0.88 ALPL (0.43) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11459578 0.87 MMP2 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL15634059 0.86 ACACB (0.38) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL18827241 0.86 PTGS1 (0.45) PTGS1PTGS2ALPIALPLCA2
SCHEMBL11450799 0.85 CA2 (0.45) PTGS1PTGS2NOTUMRARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14800 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739114-A1 HERBICIDAL MIXTURES COMPRISING SYNTHETIC AUXINS AND USES THEREOF Adama Agan Ltd. (IL) 2026-05-13 EP claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US claimed
EP-4601471-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES Corteva Agriscience LLC (US) 2025-08-20 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-4593598-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND BEFLUBUTAMID FMC Corporation (US) 2025-08-06 EP claimed
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof BASF Agro B.V. (NL) 2025-08-05 US claimed
CN-1076585-A Synergistic herbicides and safeners HOECHST AG (DE) 1993-09-29 CN claimed
WO-1993005655-A1 SYNERGISTIC HERBICIDAL COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-01 WO claimed
EP-0456334-A2 Heribicidal composition with synergistic activity SCHERING AKTIENGESELLSCHAFT (DE) 1991-11-13 EP claimed
CN-1055462-A Has synergistic new herbicidal composition SCHERING AG (DE) 1991-10-23 CN claimed
WO-1991005469-A2 HERBICIDAL COMBINATIONS OF ACTIVE SUBSTANCES HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-02 WO claimed
CN-1050970-A Herbicidal active substance combination agent HOECHST AG (DE) 1991-05-01 CN claimed
CN-1034467-A Benfuresate (benfure sate) composition SCHERING AG (DE) 1989-08-09 CN claimed
EP-0326305-A2 Benfuresate mixtures SCHERING AKTIENGESELLSCHAFT (DE) 1989-08-02 EP claimed
US-4292068-A APPLYING 2,3-DIHYDRO-3,3-DIMETHYLBENZOFURAN-5-YL ETHANESULFONATE TO COMBAT SUBTERRANEAN-PROPAGATING WEEDS FISONS LIMITED (GB) 1981-09-29 US claimed
US-4162154-A BENZOFURAN DERIVATIVES FISONS LIMITED (GB) 1979-07-24 US claimed