Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCL6 | P41182 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178856 | 0.86 | HTT (0.65) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL27904491 | 0.84 | HTT (0.53) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL960876 | 0.80 | HTT (0.52) | HTTALOX15POLBUSP2PTPN7 | |
| SCHEMBL27930399 | 0.79 | HTT (0.59) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL946948 | 0.78 | HTT (0.75) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL4138642 | 0.78 | HTT (0.68) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL4211579 | 0.77 | TP53 (0.71) | HTTALOX15TP53POLBUSP2 | |
| Hydrochloric Acid SCHEMBL946927 | 0.76 | HTT (0.72) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL4210667 | 0.75 | BCL6 (0.64) | HTTALOX15TP53POLBUSP2 | |
| SCHEMBL11174391 | 0.74 | HTT (1.00) | HTTALOX15TP53POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312333-B2 | SK channel positive allosteric modulators | CHAPMAN UNIVERSITY (US) | 2025-05-27 | — | — | US | disclosed |
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | CHAPMAN UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-101938988-B | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2250998-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | KCNN1, KCNN4, KCNN2 | HTT 1211/4885ALOX15 3494/4885TP53 4111/4885 |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | HTT 3402/4885ALOX15 510/4885TP53 4458/4885 |
| US-12312333-B2 | SK channel positive allosteric modulators | KCNN1, KCNN4, KCNN2 | HTT 1180/4885ALOX15 3570/4885TP53 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.