Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.55 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL946927 | 0.98 | HTT (0.72) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL4138642 | 0.91 | HTT (0.68) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL11186961 | 0.88 | HTT (0.66) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL4207277 | 0.88 | SMN1; SMN2 (0.66) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL30421872 | 0.86 | HTT (0.64) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL5698625 | 0.86 | HTT (0.64) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL11174391 | 0.86 | HTT (1.00) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL12918505 | 0.83 | LMNA (0.64) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL5501899 | 0.83 | ALOX15 (1.00) | HTTALOX15TP53LMNAALDH1A1 | |
| SCHEMBL948912 | 0.83 | HTT (0.59) | HTTALOX15TP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293300-A1 | SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD | SHISEIDO COMPANY, LTD. (JP) | 2024-09-05 | — | — | US | disclosed |
| JP-2024092959-A | COSMETIC | 株式会社 資生堂 | 2024-07-08 | — | — | JP | disclosed |
| WO-2024142899-A1 | COSMETIC | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024142837-A1 | COSMETIC | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| CN-118252771-A | Cosmetic material | 株式会社资生堂 | 2024-06-28 | — | — | CN | disclosed |
| WO-2024135395-A1 | COSMETIC PREPARATION | 株式会社 資生堂 | 2024-06-27 | — | — | WO | disclosed |
| CN-117545457-A | Cosmetic for skin penetration | 株式会社资生堂 | 2024-02-09 | — | — | CN | disclosed |
| CN-117545456-A | Cosmetic for skin permeation and method for producing cosmetic for skin permeation | 株式会社资生堂 | 2024-02-09 | — | — | CN | disclosed |
| WO-2023002873-A1 | SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD | 株式会社資生堂 | 2023-01-26 | — | — | WO | disclosed |
| WO-2023002872-A1 | COSMETIC FOR SKIN PERMEATION | 株式会社資生堂 | 2023-01-26 | — | — | WO | disclosed |
| US-20130045173-A1 | Method For Inhibiting Melanin Production And Whitening Skin With Pyrimidlypyrazole Compounds Or Pharmaceutically Acceptable Salts Thereof | SHISEDIO COMPANY LTD. (JP) | 2013-02-21 | — | — | US | disclosed |
| US-8324234-B2 | Method for inhibiting melanin production and whitening skin with pyrimidylpyrazole compounds or pharmaceutically acceptable salts thereof | SHISEIDO COMPANY LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8324234-B2 | Method for inhibiting melanin production and whitening skin with pyrimidylpyrazole compounds or pharmaceutically acceptable salts thereof | SHISEIDO COMPANY LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8324234-B2 | Method for inhibiting melanin production and whitening skin with pyrimidylpyrazole compounds or pharmaceutically acceptable salts thereof | SHISEIDO COMPANY LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120283441-A1 | Method For Producing Pyrimidinylpyrazole Compounds | SHISEIDO COMPANY, LTD. (JP) | 2012-11-08 | — | — | US | disclosed |
| US-20120283441-A1 | Method For Producing Pyrimidinylpyrazole Compounds | SHISEIDO COMPANY, LTD. (JP) | 2012-11-08 | — | — | US | disclosed |
| US-20110003838-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20110003838-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20110003838-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2250999-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003838-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, MCHR1 | HTT 1999/4885ALOX15 124/4885TP53 4325/4885 |
| US-20120283441-A1 | Method For Producing Pyrimidinylpyrazole Compounds | DCK, IFNG, QDPR | HTT 2431/4885ALOX15 4708/4885TP53 3535/4885 |
| US-20240293300-A1 | SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD | CUTA, SLC6A12, DSG1 | HTT 3707/4885ALOX15 3356/4885TP53 1716/4885 |
| US-20130045173-A1 | Method For Inhibiting Melanin Production And Whitening Skin With Pyrimidlypyrazole Compounds Or Pharmaceutically Acceptable Salts Thereof | TYR, MC1R, TH | HTT 1999/4885ALOX15 238/4885TP53 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.