Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617996 | 1.00 | IMPDH2 (0.33) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8935340 | 0.88 | IMPDH2 (0.35) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8935350 | 0.88 | IMPDH2 (0.35) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL10916603 | 0.78 | IMPDH2 (0.33) | IMPDH2IMPDH1 | |
| SCHEMBL10916627 | 0.78 | IMPDH2 (0.33) | IMPDH2IMPDH1 | |
| SCHEMBL10405563 | 0.78 | IMPDH2 (0.35) | IMPDH2IMPDH1 | |
| SCHEMBL10592486 | 0.76 | IMPDH2 (0.31) | IMPDH2IMPDH1 | |
| SCHEMBL10406721 | 0.75 | PTPN1 (0.51) | — | |
| SCHEMBL8563125 | 0.75 | IMPDH2 (0.49) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8564172 | 0.74 | IMPDH2 (0.41) | IMPDH2IMPDH1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4283530-A | — | — | None | — | — | JP | disclosed |
| JP-H04283530-A | PRODUCTION OF 4-SUBSTITUTED-2-METHYL-1,2-BUTANEDIOL DERIVATIVE | KURARAY CO LTD | 1992-10-08 | — | — | JP | disclosed |
| EP-0129252-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE HYDROQUINONE DERIVATIVES AND OF D-ALPHA-TOCOPHEROL | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-08 | — | — | EP | disclosed |
| EP-0257503-B1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE HYDROQUINONE DERIVATIVES AND D-ALPHA-TOCOPHEROL | F. HOFFMANN-LA ROCHE AG (CH) | 1990-05-23 | — | — | EP | disclosed |
| US-4904823-A | Hydroquinone derivatives and a process for their preparation | HOFFMANN-LA ROCHE INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0173142-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE DERIVATIVES OF HYDROQUINONE | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-05-31 | — | — | EP | disclosed |
| US-4824972-A | Hydroquinone derivatives | HOFFMANN-LAROCHE INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-4808736-A | Process for the preparation of hydroquinone derivatives and d-α-tocopherol | HOFFMANN-LAROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4743696-A | Hydroquinone derivatives and a process for their preparation | HOFFMANN-LA ROCHE INC. (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0257503-A1 | Process for the production of optically active hydroquinone derivatives and d-alpha-tocopherol | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-02 | — | — | EP | disclosed |
| US-4709055-A | (Alkoxy-methyl)-phenyl-methyl-epoxybutanes | HOFFMANN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | disclosed |
| US-4689427-A | Hydroquinone derivatives useful in the production of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1987-08-25 | — | — | US | disclosed |
| US-4675421-A | Hydroquinone derivatives and a process for their preparation | HOFFMANN-LA ROCHE INC. (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0065368-B1 | A PROCESS FOR PREPARING CHROMANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |
| EP-0183042-A2 | Process for the preparation of hydrochinone derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1986-06-04 | — | — | EP | disclosed |
| US-4582919-A | Process for the manufacture of optically active compounds | HOFFMANN-LA ROCHE INC. (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0173142-A2 | Process for the preparation of optically active derivatives of hydroquinone | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-03-05 | — | — | EP | disclosed |
| EP-0129252-A2 | Process for the preparation of optically active hydroquinone derivatives and of d-alpha-tocopherol | F. HOFFMANN-LA ROCHE AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| US-4424389-A | Synthesis of 6-hydroxychroman-2-methanol derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-01-03 | — | — | US | disclosed |
| EP-0065368-A1 | A process for preparing chromans | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-11-24 | — | — | EP | disclosed |