Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 7/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564172 | 0.89 | IMPDH2 (0.41) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL1784681 | 0.87 | IMPDH1 (0.40) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8570251 | 0.86 | IMPDH2 (0.41) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL9549629 | 0.81 | CA2 (0.46) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8935340 | 0.78 | IMPDH2 (0.35) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8935350 | 0.78 | IMPDH2 (0.35) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL1783169 | 0.77 | HTR2A (0.46) | IMPDH2IMPDH1 | |
| SCHEMBL10405923 | 0.77 | IMPDH2 (0.33) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL1820953 | 0.77 | IMPDH2 (0.32) | IMPDH2IMPDH1 | |
| SCHEMBL1242706 | 0.76 | TNKS2 (0.35) | IMPDH2IMPDH1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549366-B1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0549366-A1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |