SCHEMBL9618282

SCHEMBL9618282

CCCCCOC1CCCCC1(O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.41
SLC6A4 P31645 12/20 0.39
OPRM1 P35372 8/20 0.39
SLC6A2 P23975 11/20 0.39
KMT2A Q03164 4/20 0.39
SLC22A1 O15245 3/20 0.39
MEN1 O00255 3/20 0.39
OPRD1 P41143 2/20 0.39
OPRK1 P41145 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC6A3 Q01959 1/20 0.36
NR5A1 Q13285 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28740691 0.80 SLC6A2 (0.41) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL14842579 0.77 CNR2 (0.40) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL28002157 0.75 SLC6A4 (0.47) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL4989694 0.71 SLC6A2 (0.51) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL11465118 0.69 MAPT (0.54) SLC6A4OPRM1SLC6A2KMT2AMEN1
SCHEMBL4818520 0.68 SLC6A2 (0.45) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL4818516 0.68 SLC6A2 (0.45) SLC6A9SLC6A4OPRM1SLC6A2KMT2A
SCHEMBL547562 0.68 OPRM1 (0.41) SLC6A4OPRM1SLC6A2KMT2AOPRD1
SCHEMBL150032 0.68 SLC6A4 (0.73) SLC6A4OPRM1SLC6A2KMT2ASLC22A1
SCHEMBL547417 0.68 OPRM1 (0.41) SLC6A4OPRM1SLC6A2KMT2AOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4091047-A None JP disclosed
JP-H0491047-A OPTICALLY ACTIVE 1,2-DIPHENYLCYLOHEXANE-1,2-DIOL AND ITS PRODUCTION MITSUI TOATSU CHEM INC 1992-03-24 JP disclosed