SCHEMBL961838

SCHEMBL961838

CCCC[Sn](CCCC)CCCCc1ccccc1C(=O)NN

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.42
TSHR P16473 1/20 0.42
CTSD P07339 2/20 0.41
HPGD P15428 1/20 0.40
SLC16A3 O15427 4/20 0.40
LIPG Q9Y5X9 1/20 0.39
LMNA P02545 1/20 0.39
KDR P35968 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 2/20 0.38
ADRB2 P07550 1/20 0.38
P2RX7 Q99572 1/20 0.37
NAAA Q02083 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1545821 0.88 HTT (0.49) HTTTSHRCTSDSLC16A3LIPG
SCHEMBL4433080 0.87 LIPG (0.51) HTTTSHRCTSDSLC16A3LIPG
SCHEMBL4054015 0.87 HTT (0.50) HTTTSHRCTSDHPGDSLC16A3
SCHEMBL30286812 0.80 CTSD (0.51) HTTTSHRCTSDLMNAKDR
SCHEMBL15923268 0.76 HTT (0.49) HTTTSHRHPGDSLC16A3LIPG
SCHEMBL28960300 0.75 PPARA (0.46) HTTTSHRLIPGLMNAALDH1A1
SCHEMBL7589245 0.75 HTT (0.45) HTTTSHRSLC16A3LIPGLMNA
SCHEMBL3135538 0.75 CTSD (0.56) HTTTSHRCTSDHPGDLMNA
SCHEMBL11039198 0.75 LIPG (0.51) HTTTSHRHPGDSLC16A3LIPG
SCHEMBL27690336 0.75 LIPG (0.51) HTTTSHRSLC16A3LIPGNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-20130289165-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8389641-B2 Modified diene rubber, production method thereof, and rubber composition and tire using the rubber BRIDGESTONE CORPORATION (JP) 2013-03-05 US disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed