Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044887 | 0.85 | IDO1 (0.56) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL29250836 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20150092 | 0.80 | ALOX15 (0.50) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11073181 | 0.80 | CYP3A4 (0.54) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21863515 | 0.80 | GABRA1 (0.38) | CYP3A4CYP1A2ALDH1A1LMNAMAPT | |
| SCHEMBL928068 | 0.80 | TSHR (0.48) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL1819866 | 0.78 | TSHR (0.47) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22797014 | 0.77 | CYP3A4 (0.51) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8333563 | 0.77 | CYP3A4 (0.51) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL28362336 | 0.77 | TSHR (0.46) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | claimed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | claimed |
| JP-4298524-A | — | — | None | — | — | JP | disclosed |
| US-20210061831-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2021-03-04 | — | — | US | disclosed |
| JP-H04298524-A | EPOXY RESIN COMPOSITION AND ITS CURING METHOD | TEXACO CHEM CO | 1992-10-22 | — | — | JP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0483953-A1 | 1-Isopropyl-2-tolylimidazole as an epoxy resin curative | TEXACO CHEMICAL COMPANY (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5086155-A | Lengthy pot life at ambient temperatures; stability; resistance to heat, chemicals and moisture | TEXACO CHEMICAL COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061831-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | CYP3A4 4332/4885CYP1A2 4427/4885CYP2D6 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.