Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558996 | 0.84 | CASR (0.41) | MAPTPLA2G2AEPHX1PLA2G10SLC6A3 | |
| SCHEMBL9558477 | 0.78 | PLA2G2A (0.45) | MAPTCYP3A4PLA2G2APLA2G10CAPN1 | |
| SCHEMBL9558864 | 0.77 | CCKBR (0.48) | CYP3A4PLA2G2APLA2G10 | |
| SCHEMBL9558991 | 0.70 | PLA2G2A (0.42) | CYP3A4PLA2G2APLA2G10 | |
| SCHEMBL9558971 | 0.69 | ANPEP (0.46) | MAPTCYP3A4PLA2G2APLA2G10CAPN1 | |
| SCHEMBL20087750 | 0.68 | SLC6A2 (0.46) | MAPTCYP3A4EPHX1FAAHSLC6A3 | |
| SCHEMBL20087747 | 0.68 | SLC6A2 (0.46) | MAPTCYP3A4EPHX1FAAHSLC6A3 | |
| SCHEMBL9361081 | 0.67 | ANPEP (0.56) | MAPTCYP3A4ANPEP | |
| SCHEMBL5950937 | 0.66 | BACE1 (0.50) | MAPTCYP3A4EPHX1PLA2G10ANPEP | |
| SCHEMBL5950938 | 0.66 | BACE1 (0.50) | MAPTCYP3A4EPHX1PLA2G10ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4095063-A | — | — | None | — | — | JP | disclosed |
| JP-H0495063-A | NAPHTHYLTHIOALKYLCARBOXYLIC ACID DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1992-03-27 | — | — | JP | disclosed |