Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558971 | 0.87 | ANPEP (0.46) | PLA2G2APLA2G10ANPEPALDH1A1MAPT | |
| SCHEMBL9558884 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10ANPEPBACE1 | |
| SCHEMBL9558499 | 0.84 | CASP1 (0.41) | PLA2G2APLA2G10ANPEPALDH1A1LMNA | |
| SCHEMBL9645693 | 0.84 | SLC1A1 (0.43) | ALDH1A1MAPTLMNACYP3A4CYP2C9 | |
| SCHEMBL9645703 | 0.82 | L3MBTL1 (0.42) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558864 | 0.81 | CCKBR (0.48) | PLA2G2APLA2G10ALDH1A1LMNACYP3A4 | |
| SCHEMBL9618400 | 0.78 | MAPT (0.43) | PLA2G2APLA2G10ANPEPMAPTCYP3A4 | |
| SCHEMBL9558996 | 0.78 | CASR (0.41) | PLA2G2APLA2G10MAPT | |
| SCHEMBL5279103 | 0.77 | ANPEP (0.48) | PLA2G2APLA2G10ANPEPCYP3A4CYP2C9 | |
| SCHEMBL9365053 | 0.77 | EPHX1 (0.46) | ANPEPALDH1A1MAPTLMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177069-A | Cholecystokinin inhibitor, pancreatic antisecretory agent | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0433064-A1 | Naphthylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1991-06-19 | — | — | EP | disclosed |