SCHEMBL9618429

SCHEMBL9618429

COc1ccc2cc(Oc3cccc(C(=O)O)c3)ccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
AKR1C3 P42330 1/20 0.67
KMO O15229 1/20 0.60
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
ALDH1A1 P00352 1/20 0.59
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MITF O75030 1/20 0.56
POLB P06746 2/20 0.56
PPARG P37231 2/20 0.56
CYP2C9 P11712 1/20 0.56
PGR P06401 1/20 0.56
PARP1 P09874 1/20 0.56
MRGPRX4 Q96LA9 1/20 0.55
MEN1 O00255 1/20 0.55
CASP3 P42574 1/20 0.55
KMT2A Q03164 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867923 0.92 AKR1C3 (0.73) KDM4EAKR1C3KMOCES2CES1
SCHEMBL2857877 0.90 AKR1C3 (0.77) KDM4EAKR1C3KMOCES2CES1
SCHEMBL63427 0.88 CES2 (0.74) KDM4EAKR1C3CES2CES1NPC1
SCHEMBL29351426 0.88 CES2 (0.74) KDM4EAKR1C3CES2CES1NPC1
SCHEMBL6827745 0.88 CES2 (0.74) KDM4EAKR1C3CES2CES1NPC1
SCHEMBL1448094 0.86 CES2 (0.71) KDM4EAKR1C3CES2CES1NPC1
Hydrochloric Acid SCHEMBL30142542 0.86 CES2 (0.71) KDM4EAKR1C3CES2CES1NPC1
Hydrochloric Acid SCHEMBL5773812 0.86 CES2 (0.71) KDM4EAKR1C3CES2CES1NPC1
SCHEMBL10403563 0.86 CES2 (0.71) KDM4EAKR1C3CES2CES1NPC1
Water SCHEMBL27893543 0.86 CES2 (0.71) KDM4EAKR1C3CES2CES1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4300850-A None JP disclosed
US-5169978-A Polyester monomer SOCIETE ATOCHEM (FR) 1992-12-08 US disclosed
JP-H04300850-A NAPHTHYLOXYBENZOIC ACID AND NAPHTHYLOXYNAPHTHOIC ACID DERIVATIVES, AND THEIR SYNTHESIZING METHOD ELF ATOCHEM SA 1992-10-23 JP disclosed