Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | KMO | O15229 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867923 | 0.91 | AKR1C3 (0.73) | AKR1C3ALDH1A1KMOKDM4ERAB9A | |
| SCHEMBL1042631 | 0.91 | AKR1C3 (0.92) | AKR1C3ALDH1A1KMOKDM4ERAB9A | |
| SCHEMBL30266789 | 0.91 | AKR1C3 (0.92) | AKR1C3ALDH1A1KMOKDM4ERAB9A | |
| SCHEMBL9618429 | 0.90 | KDM4E (0.70) | AKR1C3ALDH1A1KMOKDM4ERAB9A | |
| SCHEMBL29546656 | 0.89 | AKR1C3 (0.96) | AKR1C3KMOKDM4ERAB9ANPC1 | |
| SCHEMBL28701196 | 0.89 | AKR1C3 (0.96) | AKR1C3KMOKDM4ERAB9ANPC1 | |
| SCHEMBL4320685 | 0.89 | AKR1C3 (0.96) | AKR1C3KMOKDM4ERAB9ANPC1 | |
| P-Anisic Acid SCHEMBL28062329 | 0.88 | CA1 (0.71) | AKR1C3ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL30307447 | 0.87 | AKR1C3 (0.85) | AKR1C3KMOKDM4ERAB9ANPC1 | |
| SCHEMBL16429240 | 0.87 | AKR1C3 (0.85) | AKR1C3KMOKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196214-B2 | Process for arylamine production | XEROX CORPORATION (US) | 2007-03-27 | — | — | US | claimed |
| US-20060111582-A1 | Process for arylamine production | XEROX CORPORATION (US) | 2006-05-25 | — | — | US | claimed |
| EP-3112343-B1 | AMIDE DERIVATIVES | UNIV TOHOKU (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-11040937-B2 | Amide derivative | TOHOKU UNIVERSITY (JP) | 2021-06-22 | — | — | US | disclosed |
| CN-106029632-B | Amide derivatives | 国立大学法人东北大学 | 2019-06-21 | — | — | CN | disclosed |
| WO-2017063754-A1 | CONFORMATIONALLY CONSTRAINED MACROCYCLIC COMPOUNDS AS PIN1 MODULATORS | POLYPHOR AG (CH) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017063755-A1 | CONFORMATIONALLY CONSTRAINED MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2017-04-20 | — | — | WO | disclosed |
| EP-3112343-A1 | AMIDE DERIVATIVES | Tohoku University (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368860-A1 | AMIDE DERIVATIVE | TOHOKU UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
| CN-106029632-A | Amide derivatives | 国立大学法人东北大学 | 2016-10-12 | — | — | CN | disclosed |
| US-9149019-B2 | Method of eliminating cat urine odor | JMR, LC (US) | 2015-10-06 | — | — | US | disclosed |
| US-5235064-A | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5214204-A | Inhibitors of biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1993002037-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1993-02-04 | — | — | WO | disclosed |
| US-5171882-A | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| US-4992576-A | Antiinflammatory, antiallergens | ELI LILLY AND COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0276064-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4946926-A | INJECTION MOLDED ARTICLE, FIBER OR FILM OF A POLYLACTONE | THE DOW CHEMICAL COMPANY (US) | 1990-08-07 | — | — | US | disclosed |
| US-4945150-A | Melt processable thermotropic aromatic copolyester derived from hydroxy phenoxy benzoic acids and hydroxy benzoic acid | THE DOW CHEMICAL COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276064-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368860-A1 | AMIDE DERIVATIVE | ARG1, PTMS, MLX | AKR1C3 974/4885ALDH1A1 1014/4885KMO 4846/4885 |
| US-11040937-B2 | Amide derivative | ARG1, PTMS, MLX | AKR1C3 974/4885ALDH1A1 1014/4885KMO 4846/4885 |
| US-20060111582-A1 | Process for arylamine production | AOC2, UFM1, TYR | AKR1C3 2668/4885ALDH1A1 1029/4885KMO 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.