Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618812 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAPTGS2KMT2AMEN1 | |
| SCHEMBL9619097 | 0.87 | L3MBTL1 (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9619093 | 0.87 | L3MBTL1 (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9618769 | 0.87 | MAPT (0.35) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9618876 | 0.86 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL9618852 | 0.85 | ALDH1A1 (0.34) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9618856 | 0.85 | ALDH1A1 (0.34) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10551845 | 0.85 | MAPT (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9618931 | 0.83 | L3MBTL1 (0.43) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL9618928 | 0.83 | L3MBTL1 (0.43) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236916-B1 | N-ARYLTETRAHYDROPHTHALIMIDE DERIVATIVES AND THEIR PRECURSORS | BASF Aktiengesellschaft (DE) | 1992-01-08 | — | — | EP | disclosed |
| US-4844733-A | PRE- AND POSTEMERGENCE | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0236916-A2 | N-aryltetrahydrophthalimide derivatives and their precursors | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |