Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618931 | 1.00 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL9618903 | 0.96 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TDP1FAAHTSHR | |
| SCHEMBL9618852 | 0.93 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1TDP1SMN1; SMN2HPGD | |
| SCHEMBL9618856 | 0.93 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1TDP1SMN1; SMN2HPGD | |
| SCHEMBL9618983 | 0.90 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL9619093 | 0.88 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL9619097 | 0.88 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL9618934 | 0.86 | EPHX2 (0.37) | L3MBTL1ALDH1A1TDP1TSHREPHX2 | |
| SCHEMBL9618809 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL9618812 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236916-B1 | N-ARYLTETRAHYDROPHTHALIMIDE DERIVATIVES AND THEIR PRECURSORS | BASF Aktiengesellschaft (DE) | 1992-01-08 | — | — | EP | disclosed |
| US-4844733-A | PRE- AND POSTEMERGENCE | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0236916-A2 | N-aryltetrahydrophthalimide derivatives and their precursors | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |