Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618983 | 0.96 | ALDH1A1 (0.37) | EPHX2ALDH1A1MGLLTDP1L3MBTL1 | |
| SCHEMBL9618806 | 0.91 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9618903 | 0.90 | ALDH1A1 (0.39) | EPHX2PRSS1PRSS2PRSS3NAAA | |
| SCHEMBL9618928 | 0.86 | L3MBTL1 (0.43) | EPHX2ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL10553698 | 0.84 | ALDH1A1 (0.37) | LMNAALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL9618769 | 0.83 | MAPT (0.35) | LMNAALDH1A1L3MBTL1 | |
| SCHEMBL10549353 | 0.82 | APP (0.36) | LMNAALDH1A1TSHRAPP | |
| SCHEMBL9618924 | 0.81 | GSTP1 (0.34) | LMNAALDH1A1TSHR | |
| SCHEMBL9618852 | 0.81 | ALDH1A1 (0.34) | LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9618856 | 0.81 | ALDH1A1 (0.34) | LMNAALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236916-B1 | N-ARYLTETRAHYDROPHTHALIMIDE DERIVATIVES AND THEIR PRECURSORS | BASF Aktiengesellschaft (DE) | 1992-01-08 | — | — | EP | disclosed |
| US-4844733-A | PRE- AND POSTEMERGENCE | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0236916-A2 | N-aryltetrahydrophthalimide derivatives and their precursors | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |