Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 18/20 | 0.67 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9618940 | 0.85 | POLB (0.59) | ABCB1 | |
| SCHEMBL7754052 | 0.84 | ABCB1 (0.69) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL8030271 | 0.83 | POLB (0.60) | ABCB1 | |
| SCHEMBL9627874 | 0.82 | ABCB1 (0.65) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL30109393 | 0.81 | ABCB1 (0.63) | ABCB1 | |
| SCHEMBL11155287 | 0.80 | ABCB1 (0.62) | ABCB1SCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL1702139 | 0.80 | ABCB1 (0.65) | ABCB1 | |
| Bicarbonate SCHEMBL27740097 | 0.80 | ABCB1 (0.61) | ABCB1 | |
| SCHEMBL6012120 | 0.79 | ABCB1 (0.68) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL2048117 | 0.79 | ABCB1 (0.68) | ABCB1SCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279475-B1 | BENZOPHENONE DERIVATIVES | WARD BLENKINSOP AND COMPANY LIMITED (GB) | 1992-01-15 | — | — | EP | disclosed |
| EP-0279475-A2 | Benzophenone derivatives | WARD BLENKINSOP AND COMPANY LIMITED (GB) | 1988-08-24 | — | — | EP | disclosed |