Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10943012 | 0.92 | CA1 (0.52) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Bicarbonate SCHEMBL6814371 | 0.92 | CA1 (0.52) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Propionic Acid SCHEMBL2370939 | 0.90 | CA2 (0.50) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Bicarbonate SCHEMBL28065295 | 0.88 | CA1 (0.48) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Acetic Acid SCHEMBL27695161 | 0.86 | CA1 (0.47) | CA1CA2MAPK1NFKB1CYP3A4 | |
| SCHEMBL626822 | 0.86 | CA2 (0.48) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Phosphine SCHEMBL27975608 | 0.84 | CA2 (0.47) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL931428 | 0.84 | CA1 (0.45) | CA1CA2CES2CES1 | |
| Acrylic Acid SCHEMBL27681921 | 0.84 | CA1 (0.45) | CA1CA2MAPK1NFKB1CYP3A4 | |
| Bicarbonate SCHEMBL7572929 | 0.83 | CA1 (0.54) | CA1CA2MAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117728109-A | Casting film liquid, lithium battery composite diaphragm and preparation method thereof | 上海大学 | 2024-03-19 | — | — | CN | claimed |
| EP-2905361-B1 | METHOD OF FORMING A METAL COATING | TOYOTA MOTOR CO LTD (JP) | 2022-01-05 | — | — | EP | disclosed |
| EP-2905361-A1 | ELECTROPLATING CELL, METAL COATING AND METHOD OF FORMING THE SAME | Toyota Jidosha Kabushiki Kaisha (JP) | 2015-08-12 | — | — | EP | disclosed |
| EP-0291074-B1 | PROCESS FOR PRODUCING QUATERNARY SALTS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4892944-A | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0291074-A2 | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-11-17 | — | — | EP | disclosed |