Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL931428

CCCC[P+](C)(CCCC)CCCC.O=C([O-])C(F)(F)F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.45
CA2 P00918 4/20 0.44
FAAH O00519 8/20 0.42
CCR5 P51681 3/20 0.41
CES1 P23141 5/20 0.41
CES2 O00748 3/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3785764 0.92 FAAH (0.47) CA1CA2FAAHCCR5CES1
Trifluoroacetic Acid SCHEMBL3773331 0.92 FAAH (0.47) CA1CA2FAAHCCR5CES1
Trifluoroacetic Acid SCHEMBL3685262 0.85 DNM1 (0.46) CA1CA2FAAHCES1CES2
Bicarbonate SCHEMBL9619217 0.84 CA1 (0.54) CA1CA2CES1CES2
Bicarbonate SCHEMBL6814371 0.82 CA1 (0.52) CA1CA2CES1CES2
Acetic Acid SCHEMBL10943012 0.82 CA1 (0.52) CA1CA2CES1CES2
Propionic Acid SCHEMBL2370939 0.80 CA2 (0.50) CA1CA2
Trifluoroacetic Acid SCHEMBL3770244 0.80 DNM1 (0.58) CA1CA2FAAHCCR5CES1
Bicarbonate SCHEMBL28065295 0.78 CA1 (0.48) CA1CA2
Trifluoroacetic Acid SCHEMBL11435310 0.78 DNM1 (0.54) CA1CA2FAAHCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539986-A2 CATALYTIC SYSTEM CONTAINING IONIC LIQUIDS AND A PROCESS FOR PRODUCING HYDROGEN FROM PLASTIC MATERIALS USING SAID CATALYTIC SYSTEM Fundación Centro de Investigación Cooperativa de Energías Alternativas, CIC Energigune Fundazioa (ES) 2025-04-23 EP disclosed
WO-2023242335-A2 CATALYTIC SYSTEM CONTAINING IONIC LIQUIDS AND A PROCESS FOR PRODUCING HYDROGEN FROM PLASTIC MATERIALS USING SAID CATALYTIC SYSTEM FUNDACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA DE ENERGÍAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA (ES) 2023-12-21 WO disclosed
US-9175021-B2 Process for the preparation of perfluoroalkylcyano- or perfluoroalkylcyanofluoroborates MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-20150166588-A1 PROCESS FOR THE PREPARATION OF PERFLUOROALKYLCYANO- OR PERFLUOROALKYLCYANOFLUOROBORATES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2015-06-18 US disclosed
US-8927757-B2 Process for the preparation of perfluoroalkylcyano- or perfluoroalkylcyanofluoroborates MERCK PATENT GMBH (DE) 2015-01-06 US disclosed
US-20120309981-A1 PROCESS FOR THE PREPARATION OF PERFLUOROALKYLCYANO- OR PERFLUOROALKYLCYANOFLUOROBORATES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 US disclosed
WO-2011000490-A2 SYNTHESIS OF IONIC LIQUIDS MERCK PATENT GMBH (DE) 2011-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309981-A1 PROCESS FOR THE PREPARATION OF PERFLUOROALKYLCYANO- OR PERFLUOROALKYLCYANOFLUOROBORATES SLCO4C1, SLCO2B1, PFAS CA1 1560/4885CA2 225/4885FAAH 1753/4885
US-20150166588-A1 PROCESS FOR THE PREPARATION OF PERFLUOROALKYLCYANO- OR PERFLUOROALKYLCYANOFLUOROBORATES SLCO4C1, SLCO2B1, PFAS CA1 1560/4885CA2 225/4885FAAH 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.