Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859483 | 0.80 | ADORA3 (0.61) | KDM4EMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL9704213 | 0.79 | EGFR (0.60) | KDM4EMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL9619544 | 0.77 | NPC1 (0.43) | KDM4EMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL9619520 | 0.76 | MEN1 (0.50) | KDM4EMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL5593018 | 0.76 | ACACA (0.57) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL16146442 | 0.76 | CYP1A1 (0.67) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8271638 | 0.76 | ACACA (0.66) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL27740718 | 0.75 | DYRK1A (0.67) | KDM4EMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL12306221 | 0.75 | ADORA3 (0.59) | KDM4EMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL3237986 | 0.75 | EGFR (0.60) | KDM4EMAPTALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | claimed |
| EP-0263958-B1 | 4-SUBSTITUTED-2,6-DIPHENYLPYRIDINE DERIVATIVES, USE THEREOF, PRODUCTION OF THE SAME, CHEMICAL INTERMEDIATES THEREIN AND HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4849011-A | 4-substituted-2,6-diphenylpyridine compounds and herbicide containing the same as an active ingredient | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |