Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ACACA | Q13085 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859483 | 0.85 | ADORA3 (0.61) | EGFRKDRDYRK1ANPC1RAB9A | |
| SCHEMBL3237986 | 0.83 | EGFR (0.60) | EGFRKDRDYRK1ANPC1RAB9A | |
| SCHEMBL31326814 | 0.83 | EGFR (0.60) | EGFRKDRDYRK1ANPC1RAB9A | |
| SCHEMBL8271638 | 0.80 | ACACA (0.66) | DYRK1ANPC1RAB9AKDM4EMEN1 | |
| SCHEMBL28342829 | 0.80 | ACHE (0.58) | EGFRKDRNPC1RAB9AKDM4E | |
| SCHEMBL12264964 | 0.80 | MEN1 (0.55) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL12306221 | 0.79 | ADORA3 (0.59) | EGFRKDRDYRK1ANPC1RAB9A | |
| SCHEMBL28196806 | 0.79 | ACACA (0.64) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL9619331 | 0.79 | KDM4E (0.54) | EGFRKDRDYRK1ANPC1RAB9A | |
| SCHEMBL4347032 | 0.79 | ACACA (0.64) | NPC1RAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | claimed |
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |