Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620111 | 0.80 | TDP1 (0.45) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL9619818 | 0.70 | TDP1 (0.53) | TDP1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL10631855 | 0.70 | TDP1 (0.49) | TDP1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9866407 | 0.70 | NPSR1 (0.58) | TDP1NPSR1KDM4EMAPTHPGD | |
| SCHEMBL7653937 | 0.69 | NPSR1 (0.53) | TDP1NPSR1KDM4EMAPTHPGD | |
| SCHEMBL13527924 | 0.68 | TDP1 (0.80) | TDP1KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9828402 | 0.68 | TDP1 (0.50) | TDP1NPSR1MAPTALDH1A1ALOX15 | |
| SCHEMBL5681855 | 0.68 | NPSR1 (0.59) | NPSR1KDM4EMAPTHPGDPOLB | |
| SCHEMBL10631932 | 0.68 | TDP1 (0.46) | TDP1KDM4EMAPTPOLBPKM | |
| SCHEMBL1284461 | 0.67 | NPSR1 (0.58) | TDP1NPSR1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |