Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527924 | 0.74 | TDP1 (0.80) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL9828753 | 0.74 | POLB (0.47) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL10631932 | 0.74 | TDP1 (0.46) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL9690927 | 0.73 | TDP1 (0.67) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL14466166 | 0.73 | TDP1 (0.67) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL9620111 | 0.72 | TDP1 (0.45) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL10736333 | 0.72 | GAA (0.62) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL9620034 | 0.71 | TDP1 (0.44) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL8977446 | 0.71 | ALDH1A1 (0.44) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL8922119 | 0.71 | TDP1 (0.50) | TDP1GAAALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734407-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |