SCHEMBL9619772

SCHEMBL9619772

CCS(=O)(=O)c1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HPGD P15428 1/20 0.30
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619928 0.81 GSR (0.36) LMNAALDH1A1HTTHPGD
SCHEMBL9619836 0.81 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL9620046 0.80
SCHEMBL11183261 0.79 CNR2 (0.31)
SCHEMBL9619917 0.77 LMNA (0.31) LMNA
SCHEMBL9619924 0.77
SCHEMBL10787110 0.77 LOX (0.33)
SCHEMBL10894388 0.76 CYP1A2 (0.32) LMNA
SCHEMBL9619744 0.75 ALDH1A1 (0.35) ALDH1A1ALOX15TSHRHTTL3MBTL1
SCHEMBL9619835 0.70 GSR (0.46) LMNAALDH1A1TSHRHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321784-B1 FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS BAYER AG (DE) 1992-03-18 EP disclosed
EP-0285571-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
US-4968781-A COTTON CIBA-GEIGY CORPORATION (US) 1990-11-06 US disclosed
EP-0321784-A2 Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials BAYER AG (DE) 1989-06-28 EP disclosed
EP-0285571-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1988-10-05 EP disclosed
EP-0177978-B1 NAPHTHOL AMINE DERIVATIVES BAYER AG (DE) 1988-04-20 EP disclosed
EP-0158882-B1 TRIPHENEDIOXAZINE DYES BAYER AG (DE) 1987-12-16 EP disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4680384-A PYRIMIDINE DYES CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
EP-0141776-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-07-08 EP disclosed
EP-0141776-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-15 EP disclosed
EP-0128316-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0043411-B1 REACTIVE DISAZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS CONTAINING NITROGEN AND/OR HYDROXYLE GROUPS BAYER AG (DE) 1984-07-11 EP disclosed
EP-0108924-A1 Heavy metal-containing formazane dyestuffs, methods for their preparation and their use in the dyeing and printing of fibre materials BAYER AG (DE) 1984-05-23 EP disclosed
EP-0097289-A2 Azo dyestuffs BAYER AG (DE) 1984-01-04 EP disclosed
EP-0050266-A1 Reactive disazo dyes, process for their preparation and their use in dyeing and printing materials that contain hydroxyl and/or nitrogen BAYER AG (DE) 1982-04-28 EP disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
EP-0043411-A2 Reactive disazo dyestuffs, process for their preparation and their use in dyeing and printing materials containing nitrogen and/or hydroxyle groups BAYER AG (DE) 1982-01-13 EP disclosed
US-4287342-A 2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines CIBA-GEIGY CORPORATION (US) 1981-09-01 US disclosed
US-4188483-A 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof CIBA-GEIGY CORPORATION (US) 1980-02-12 US disclosed