SCHEMBL11183261

SCHEMBL11183261

CCS(=O)(=O)c1c(Cl)nc(C(C)C)nc1Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619772 0.79 LMNA (0.33)
SCHEMBL10004578 0.68 KDM4E (0.33)
SCHEMBL26647180 0.68 CYP1A2 (0.31)
SCHEMBL4432262 0.66 PDE10A (0.41)
SCHEMBL11014187 0.65
SCHEMBL5238156 0.64 MEN1 (0.37)
SCHEMBL26646821 0.64 GABRA1 (0.36)
SCHEMBL10634989 0.64 PSIP1 (0.43)
SCHEMBL11802553 0.63 HRH4 (0.34)
SCHEMBL9619928 0.63 GSR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4413124-A 2-Alkyl-5-alkylsulfonyl-4,6-dihalopyrimidines and the production thereof CIBA-GEIGY CORPORATION (US) 1983-11-01 US disclosed
US-4412074-A 2-Alkyl-5-alkyl sulfony 1-4,6-dihalopyrimidines and the production thereof CIBA-GEIGY CORPORATION (US) 1983-10-25 US disclosed
EP-0054515-A1 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1982-06-23 EP disclosed