SCHEMBL9619954

SCHEMBL9619954

CCCC=C1OC(=O)N(c2cc(OC(C)C)c(Cl)cc2F)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 12/20 0.44
MEN1 O00255 1/20 0.37
NR1I2 O75469 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KMO O15229 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619952 0.78 PPOX (0.44) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9577463 0.77 PPOX (0.47) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL8894306 0.73 PPOX (0.46) PPOX
SCHEMBL10419790 0.73 PPOX (0.55) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL8886715 0.73 PPOX (0.44) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL10419799 0.72 PPOX (0.49) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9620064 0.71 PPOX (0.48) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9619999 0.71 PPOX (0.47) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL10420665 0.71 PPOX (0.46) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9620002 0.71 PPOX (0.45) PPOXMEN1NR1I2KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed