SCHEMBL9619960

SCHEMBL9619960

C=CS(=O)(=O)CCNC(=O)c1ccc(N)c(S(=O)(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.42
CA1 P00915 5/20 0.42
CDC25B P30305 1/20 0.39
TERT O14746 2/20 0.38
HDAC3 O15379 5/20 0.37
HDAC1 Q13547 5/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9337609 0.93 CA2 (0.39) CA2CA1CDC25BTERTHDAC3
SCHEMBL9337472 0.89 CA2 (0.43) CA2CA1CDC25BTERTHDAC3
SCHEMBL9337648 0.83 GRIN1 (0.38) CA2CA1TERTHDAC3HDAC1
SCHEMBL8300376 0.81 TSHR (0.47) CA2CA1SMN1; SMN2
SCHEMBL9170125 0.81 CA2 (0.44) CA2CA1CDC25BTERTHDAC3
SCHEMBL9619926 0.81 CA2 (0.43) CA2CA1CDC25BTERTHDAC3
SCHEMBL1373367 0.81 HDAC3 (0.50) CA2CA1HDAC3HDAC1LMNA
SCHEMBL9337283 0.79 HTT (0.49) CA2CA1LMNASMN1; SMN2
SCHEMBL1373455 0.79 SMN1; SMN2 (0.46) SMN1; SMN2
SCHEMBL9338115 0.78 SMN1; SMN2 (0.36) CA2CA1TERTHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285571-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
EP-0284568-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-5037449-A For dyeing or printing cotton or wool CIBA-GEIGY CORPORATION (US) 1991-08-06 US disclosed
US-5023325-A Colorfastness, photostability CIBA-GEIGY CORPORATION (US) 1991-06-11 US disclosed
US-5003052-A Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed
US-4968781-A COTTON CIBA-GEIGY CORPORATION (US) 1990-11-06 US disclosed
US-4952679-A PRINTING, DYEING CELLULOSE CIBA-GEIGY CORPORATION (US) 1990-08-28 US disclosed
US-4929719-A Fiber-reactive dyes containing an aniline radical which carries two different vinylsulfonyl moieties CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4918169-A COTTON CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
EP-0356394-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1990-02-28 EP disclosed
EP-0304926-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-03-01 EP disclosed
EP-0304924-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-03-01 EP disclosed
US-4786721-A DYEING OR PRINTING CELLULOSE FIBERS CIBA-GEIGY CORPORATION (US) 1988-11-22 US disclosed
EP-0285571-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1988-10-05 EP disclosed
US-4766206-A Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety CIBA-GEIGY CORPORATION (US) 1988-08-23 US disclosed