SCHEMBL1373367

SCHEMBL1373367

C=CS(=O)(=O)CCNC(=O)c1ccc(N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.50
HDAC4 P56524 3/20 0.50
HDAC1 Q13547 3/20 0.50
HDAC7 Q8WUI4 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC10 Q969S8 3/20 0.50
HDAC11 Q96DB2 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
HDAC9 Q9UKV0 3/20 0.50
HDAC5 Q9UQL6 3/20 0.50
LMNA P02545 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPK1 P28482 2/20 0.49
SLC22A2 O15244 1/20 0.49
SLC22A1 O15245 1/20 0.49
TSHR P16473 1/20 0.49
ACHE P22303 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4622480 0.85 ALDH1A1 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9338115 0.85 SMN1; SMN2 (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1373455 0.83 SMN1; SMN2 (0.46) ALDH1A1KDM4EKMT2AMEN1
SCHEMBL9619960 0.81 CA2 (0.42) HDAC3HDAC1LMNACA2CA1
SCHEMBL12040903 0.81 KDM4E (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9816071 0.79 GAA (0.43) ALDH1A1CA2CA1KMT2ACA12
SCHEMBL12515200 0.78 KDM4E (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11230329 0.78 KDM4E (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9344489 0.78 KDM4E (0.68) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8300376 0.78 TSHR (0.47) TSHRCA2CA1KMT2ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 EP disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 CN disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 US disclosed
CN-104610776-A Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO 2015-05-13 CN disclosed
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 EP disclosed
EP-1934293-B1 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-07-18 EP disclosed
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 US disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 US disclosed
EP-1789499-B1 DYE MIXTURES OF FIBRE-REACTIVE AZO DYES PRODUCTION AND USE THEREOF DYSTAR COLOURS DEUTSCHLAND (DE) 2011-03-23 EP disclosed
EP-0641838-A1 Reactive dye-stuffs on basis of a substituted barbituric acid BAYER AG (DE) 1995-03-08 EP disclosed
EP-0382111-B1 Copper complex-formazane compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1994-06-08 EP disclosed
US-5023325-A Colorfastness, photostability CIBA-GEIGY CORPORATION (US) 1991-06-11 US disclosed
US-5015731-A For fibers such as wool and cellulose HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-5003052-A Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed
US-4968781-A COTTON CIBA-GEIGY CORPORATION (US) 1990-11-06 US disclosed
US-4925928-A Reactive dyes containing vinylsulfonylalkylamino bound to a bis-(triazinylamino)-benzene group CIBA-GEIGY CORPORATION (US) 1990-05-15 US disclosed
US-4845203-A FOR CELLULOSE FIBERS CIBA-GEIGY CORPORATION (US) 1989-07-04 US disclosed
US-4786721-A DYEING OR PRINTING CELLULOSE FIBERS CIBA-GEIGY CORPORATION (US) 1988-11-22 US disclosed
US-4766206-A Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety CIBA-GEIGY CORPORATION (US) 1988-08-23 US disclosed