SCHEMBL1373455

SCHEMBL1373455

C=CS(=O)(=O)CCNC(=O)c1cccc(N)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
KAT6A Q92794 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
PBRM1 Q86U86 1/20 0.40
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10629117 0.92 MEN1 (0.42) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL9338115 0.86 SMN1; SMN2 (0.36) SMN1; SMN2KDM4EKMT2A
SCHEMBL1373453 0.84 SMN1; SMN2 (0.46) SMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL1373367 0.83 HDAC3 (0.50) KDM4EALDH1A1MEN1KMT2A
SCHEMBL10408794 0.82 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL12516004 0.81 SMN1; SMN2 (0.62) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL10630944 0.81 ALDH1A1 (0.57) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL8517143 0.80 KDM4E (0.45) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL9619960 0.79 CA2 (0.42) SMN1; SMN2
SCHEMBL9341679 0.78 SMN1; SMN2 (0.45) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 EP disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 CN disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 US disclosed
CN-104610776-A Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO 2015-05-13 CN disclosed
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 EP disclosed
EP-1934293-B1 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-07-18 EP disclosed
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 US disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 US disclosed
EP-1789499-B1 DYE MIXTURES OF FIBRE-REACTIVE AZO DYES PRODUCTION AND USE THEREOF DYSTAR COLOURS DEUTSCHLAND (DE) 2011-03-23 EP disclosed
WO-2003080739-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO disclosed
WO-2003080741-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO disclosed
EP-0285571-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
EP-0284568-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-5037449-A For dyeing or printing cotton or wool CIBA-GEIGY CORPORATION (US) 1991-08-06 US disclosed
US-4968781-A COTTON CIBA-GEIGY CORPORATION (US) 1990-11-06 US disclosed
US-4952679-A PRINTING, DYEING CELLULOSE CIBA-GEIGY CORPORATION (US) 1990-08-28 US disclosed
US-4929719-A Fiber-reactive dyes containing an aniline radical which carries two different vinylsulfonyl moieties CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4918169-A COTTON CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
EP-0304924-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-03-01 EP disclosed