Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701511 | 0.76 | TDP1 (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL9701518 | 0.76 | TDP1 (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL8022411 | 0.73 | TET2 (0.48) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL28359088 | 0.70 | TET2 (0.45) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL784658 | 0.69 | TDP1 (0.45) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL4266246 | 0.69 | TDP1 (0.38) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL9619987 | 0.67 | TET2 (0.33) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL888659 | 0.66 | ALDH1A1 (0.50) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL1114512 | 0.66 | TDP1 (0.42) | TDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27536963 | 0.65 | ALOX15 (0.34) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347381-B1 | UNSATURATED BETA-KETOESTERACETALS AND THEIR APPLICATIONS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| EP-0347381-A1 | Unsaturated beta-ketoesteracetals and their applications | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |