Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698993 | 0.80 | ALDH1A1 (0.44) | TSHRHTTIDO1TDO2ALDH1A1 | |
| SCHEMBL10469475 | 0.78 | LMNA (0.47) | TSHRHTTALDH1A1GAATP53 | |
| SCHEMBL12114121 | 0.75 | GPBAR1 (0.43) | TSHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL16297247 | 0.71 | HPGD (0.41) | TSHRHTTIDO1TDO2ALDH1A1 | |
| SCHEMBL16297098 | 0.71 | NPC1 (0.38) | IDO1TDO2ALDH1A1GAAHPGD | |
| SCHEMBL8161805 | 0.70 | TSHR (0.49) | TSHRHTTIDO1TDO2ALDH1A1 | |
| SCHEMBL12115942 | 0.70 | NPC1 (0.42) | TSHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL12115670 | 0.69 | L3MBTL1 (0.48) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL8903104 | 0.69 | L3MBTL1 (0.48) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL8905045 | 0.69 | ALDH1A1 (0.54) | TSHRHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202929-B1 | SUBSTITUTED TETRAZOLINONES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0202929-A2 | Substituted tetrazolinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-26 | — | — | EP | claimed |
| EP-0202929-B1 | SUBSTITUTED TETRAZOLINONES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4956469-A | REACTION OF A TETRAZOLONE WITH AN ALKALI METAL CARBONATE FOLLOWED BY REACTION WITH A CARBAMOYL HALIDE, THESE ARE USEFUL AS HERBICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4826529-A | PLANT GROWTH REGULATORS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0202929-A2 | Substituted tetrazolinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-26 | — | — | EP | disclosed |