SCHEMBL9620523

SCHEMBL9620523

O=C(F)CCCCC(=O)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
NFKB1 P19838 2/20 0.41
TSHR P16473 1/20 0.41
PMP22 Q01453 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.35
CES1 P23141 7/20 0.35
CES2 O00748 5/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
FAAH O00519 5/20 0.33
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
AKR1B1 P15121 1/20 0.33
CYP2D6 P10635 1/20 0.33
FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2672048 0.96 TSHR (0.47) LMNANFKB1TSHRPMP22SLC22A6
SCHEMBL2672358 0.92
SCHEMBL15871917 0.84 TSHR (0.71) LMNANFKB1TSHRPMP22SLC22A6
SCHEMBL28098966 0.84 LMNA (0.38) LMNANFKB1TSHRPMP22CES1
SCHEMBL11818547 0.84
SCHEMBL2672587 0.82
SCHEMBL11177392 0.82
SCHEMBL2336034 0.82 CES2 (0.62) TSHRSLC22A6CES1CES2FAAH
SCHEMBL2326471 0.82 CES2 (0.62) TSHRSLC22A6CES1CES2FAAH
SCHEMBL22422231 0.82 PAOX (0.56) LMNANFKB1TSHRPMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111448242-B Curable fluorinated polymer composition 3M创新有限公司 2023-07-18 CN disclosed
US-20200048418-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2020-02-13 US disclosed
EP-3601408-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) Virginia Tech Intellectual Properties, Inc. (US) 2020-02-05 EP disclosed
WO-2018183280-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 2018-10-04 WO disclosed
EP-3381965-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2018-10-03 EP disclosed
US-9896547-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2018-02-20 US disclosed
EP-2925803-B1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH SCRIPPS RESEARCH INST (US) 2017-11-29 EP disclosed
US-20170218127-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE. 2017-08-03 US disclosed
US-9624344-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2017-04-18 US disclosed
US-20170002148-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE 2017-01-05 US disclosed
US-9447243-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2016-09-20 US disclosed
US-20150315340-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE 2015-11-05 US disclosed
CN-101454350-B Fluorinated surfactants 3M INNOVATIVE PROPERTIES CO 2012-06-20 CN disclosed
CN-101454350-A Fluorinated surfactants 3M INNOVATIVE PROPERTIES CO (US) 2009-06-10 CN disclosed
EP-0303382-B1 PROCESS FOR THE PREPARATION OF MESO 2,5-DIHALOADIPATES PFIZER INC. (US) 1992-03-18 EP disclosed
EP-0303382-A1 Process for the preparation of meso 2,5-dihaloadipates PFIZER INC. (US) 1989-02-15 EP disclosed
US-4736059-A Process for the preparation of meso 2,5-dihaloadipates PFIZER INC. (US) 1988-04-05 US disclosed
US-4415664-A Epiamine-based support matrix UOP INC. (US) 1983-11-15 US disclosed