Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620596 | 0.85 | CA1 (0.40) | TSHRKAT6AKMT2ACA1CA2 | |
| SCHEMBL9136969 | 0.72 | CA12 (0.44) | TSHRCA1CA2LMNAALDH1A1 | |
| SCHEMBL7025962 | 0.70 | ALDH1A1 (0.49) | TSHRKAT6ALMNAALDH1A1TP53 | |
| SCHEMBL9620517 | 0.69 | CA1 (0.40) | TSHRKMT2ACA1CA2LMNA | |
| SCHEMBL9139851 | 0.69 | CA1 (0.40) | TSHRKMT2ACA1CA2ALDH1A1 | |
| SCHEMBL31259921 | 0.69 | NFE2L2 (0.38) | KAT6AKMT2AALDH1A1 | |
| SCHEMBL5268908 | 0.69 | NFE2L2 (0.38) | KAT6AKMT2AALDH1A1 | |
| SCHEMBL11092403 | 0.69 | AR (0.36) | TSHRCA2ADRB2LMNAALDH1A1 | |
| SCHEMBL11111735 | 0.69 | ALDH1A1 (0.58) | TSHRCA1CA2LMNAALDH1A1 | |
| SCHEMBL9620878 | 0.69 | MAPT (0.48) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104441-A | HERBICIDAL SULFONAMIDES AND THEIR USE TO INFLUENCE PLANT GROWTH | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |