SCHEMBL5268908

SCHEMBL5268908

O=C=NS(=O)(=O)c1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.38
KAT6A Q92794 3/20 0.38
AKR1B1 P15121 1/20 0.38
KCNA5 P22460 1/20 0.38
KMT2A Q03164 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD11B1 P28845 1/20 0.36
GBA1 P04062 1/20 0.36
PTPRC P08575 1/20 0.35
PTPN1 P18031 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31259921 1.00 NFE2L2 (0.38) NFE2L2KAT6AAKR1B1KCNA5KMT2A
SCHEMBL6677573 0.87 GAA (0.36) KMT2AALDH1A1
SCHEMBL10864480 0.83 CXCL8 (0.39) KAT6AKCNA5KMT2AALDH1A1
SCHEMBL8798713 0.79 PKM (0.42)
SCHEMBL9870991 0.79 AKR1B1 (0.41) AKR1B1ALDH1A1
SCHEMBL395353 0.78 KMT2A (0.43) NFE2L2KMT2AL3MBTL1ALDH1A1HSD11B1
SCHEMBL11107609 0.78 GAA (0.54) KMT2AL3MBTL1TDP1
SCHEMBL10747298 0.78 LOX (0.36) ALDH1A1HSD11B1
SCHEMBL1124590 0.78 HSD11B1 (0.40) NFE2L2AKR1B1L3MBTL1ALDH1A1HSD11B1
SCHEMBL11169574 0.78 CA2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119029300-A Electrolyte and preparation method and application thereof 湖南法恩莱特新能源科技有限公司 2024-11-26 CN claimed
CN-119029300-A Electrolyte and preparation method and application thereof 湖南法恩莱特新能源科技有限公司 2024-11-26 CN disclosed
CN-119029300-A Electrolyte and preparation method and application thereof 湖南法恩莱特新能源科技有限公司 2024-11-26 CN disclosed
US-9855230-B2 Inhibitors of human immunodeficiency virus replication VIIV Healthcare UK (No.5) Limited (GB) 2018-01-02 US disclosed
US-20170304239-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2017-10-26 US disclosed
WO-2016040084-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION BRISTOL-MYERS SQUIBB COMPANY (US) 2016-03-17 WO disclosed
US-20090226819-A1 ELECTROLYTIC SOLUTION AND SECONDARY BATTERY SONY CORPORATION (JP) 2009-09-10 US disclosed
US-20090226819-A1 ELECTROLYTIC SOLUTION AND SECONDARY BATTERY SONY CORPORATION (JP) 2009-09-10 US disclosed
EP-1836189-A1 NOVEL PYRIDINE COMPOUNDS AstraZeneca AB (SE) 2007-09-26 EP disclosed
WO-2006073361-A1 NOVEL PYRIDINE COMPOUNDS ASTRAZENECA AB (SE) 2006-07-13 WO disclosed
EP-0341489-B1 Sulfonyl amino carbonyl triazolinones BAYER AG (DE) 1995-08-23 EP disclosed
US-4996208-A Pesticidal thiazolopyrimidine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
EP-0341489-A1 Sulfonyl amino carbonyl triazolinones BAYER AG (DE) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170304239-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION EIF2AK2, POLR2E, POLR2H NFE2L2 2946/4885KAT6A 1497/4885AKR1B1 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.