Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620722 | 0.96 | ACHE (0.48) | ACHE | |
| SCHEMBL9621341 | 0.83 | CHRNA7 (0.47) | ACHE | |
| SCHEMBL4859012 | 0.81 | ACHE (0.61) | ACHE | |
| SCHEMBL6794410 | 0.79 | ACHE (0.48) | ACHE | |
| SCHEMBL9620834 | 0.77 | ACHE (0.49) | ACHE | |
| SCHEMBL10701176 | 0.75 | KDM4E (0.50) | ACHE | |
| SCHEMBL9620941 | 0.75 | MAOA (0.45) | — | |
| SCHEMBL9621233 | 0.74 | NPC1 (0.46) | — | |
| SCHEMBL7820428 | 0.73 | KDM4E (0.46) | — | |
| SCHEMBL9620999 | 0.73 | ACHE (0.42) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |