Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806222 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL9620827 | 0.88 | KDM4E (0.61) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL143850 | 0.88 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL1983852 | 0.87 | CYP3A4 (0.63) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL8014076 | 0.84 | TNF (0.57) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL6937797 | 0.84 | APP (0.57) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL8010166 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL9620871 | 0.83 | DYRK1A (0.53) | ALDH1A1CYP3A4TDP1KDM4EMAPT | |
| SCHEMBL1223274 | 0.82 | APP (0.44) | ALDH1A1KDM4EMAPTGAARAB9A | |
| SCHEMBL12422442 | 0.81 | APP (0.58) | ALDH1A1CYP3A4TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |