Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620880 | 0.87 | ALDH1A1 (0.79) | ALDH1A1HPGDHTTMAPTKMT2A | |
| SCHEMBL9620749 | 0.84 | HPGD (0.74) | ALDH1A1HPGDHTTALOX12LMNA | |
| SCHEMBL28030070 | 0.83 | EPHX1 (0.73) | ALDH1A1ALOX12LMNAMAPTKMT2A | |
| SCHEMBL25517519 | 0.83 | HPGD (0.63) | ALDH1A1HPGDHTTALOX12LMNA | |
| SCHEMBL8002218 | 0.82 | HPGD (0.70) | ALDH1A1HPGDHTTALOX12LMNA | |
| SCHEMBL31388324 | 0.81 | HPGD (0.80) | ALDH1A1HPGDHTTALOX12LMNA | |
| SCHEMBL3822985 | 0.81 | HPGD (0.80) | ALDH1A1HPGDHTTALOX12LMNA | |
| SCHEMBL8970971 | 0.81 | POLB (0.70) | ALDH1A1HPGDLMNAPOLBMAPT | |
| SCHEMBL10527551 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HPGDHTTALOX12POLB | |
| SCHEMBL27736065 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HPGDHTTALOX12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306708-B1 | NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4910211-A | Containing a phenyl substituted in position 2 and an ester in position 4 | KANEBO LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0306708-A1 | Novel benzothiazole and antirheumatic agent comprising it as an active ingredient | KANEBO, LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |