SCHEMBL8970971

SCHEMBL8970971

COc1ccccc1NC(=O)c1ccc(C)cc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.70
MLYCD O95822 1/20 0.69
HPGD P15428 3/20 0.68
ALDH1A1 P00352 2/20 0.68
RAB9A P51151 4/20 0.67
NPC1 O15118 3/20 0.67
AHR P35869 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
LMNA P02545 1/20 0.67
PABPC1 P11940 1/20 0.67
APOBEC3A P31941 1/20 0.67
EIF4H Q15056 1/20 0.67
APOBEC3G Q9HC16 1/20 0.67
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
F10 P00742 1/20 0.61
MAPT P10636 1/20 0.61
KDM4E B2RXH2 1/20 0.61
P4HTM Q9NXG6 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29989592 0.88 RAB9A (0.77) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL527994 0.88 RAB9A (0.77) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL9620767 0.87 MLYCD (0.69) POLBMLYCDHPGDALDH1A1RAB9A
SCHEMBL16583906 0.87 RAB9A (0.70) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL9620772 0.87 F10 (0.81) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL96146 0.86 MLYCD (0.68) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL682871 0.86 GAA (0.68) MLYCDHPGDALDH1A1RAB9ANPC1
SCHEMBL28030070 0.86 EPHX1 (0.73) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL16681360 0.85 KMT2A (0.76) POLBMLYCDHPGDRAB9ANPC1
SCHEMBL13762076 0.84 MLYCD (0.70) MLYCDHPGDALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed
EP-0306708-B1 NOVEL BENZOTHIAZOLE AND ANTIRHEUMATIC AGENT COMPRISING IT AS AN ACTIVE INGREDIENT KANEBO, LTD. (JP) 1992-01-08 EP disclosed
US-4910211-A Containing a phenyl substituted in position 2 and an ester in position 4 KANEBO LTD. (JP) 1990-03-20 US disclosed
EP-0306708-A1 Novel benzothiazole and antirheumatic agent comprising it as an active ingredient KANEBO, LTD. (JP) 1989-03-15 EP disclosed