SCHEMBL9621391

SCHEMBL9621391

C[Si](C)(C)Oc1ccccc1CCO

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.40
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
AOC3 Q16853 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
KCNH2 Q12809 1/20 0.35
MPO P05164 1/20 0.35
HRH1 P35367 1/20 0.34
HTR1A P08908 1/20 0.34
DRD2 P14416 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7438547 0.82 NPSR1 (0.36) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL10452223 0.81 TAAR1 (0.40) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL6178459 0.80 TAAR1 (0.37) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL10584996 0.79 THRA (0.44) TAAR1
SCHEMBL29474956 0.78 TAAR1 (0.64) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL852646 0.78 TAAR1 (0.64) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL6236000 0.77 HRH1 (0.48) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL3299435 0.77 TSHR (0.38) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL3155841 0.76 IDO1 (0.34) TAAR1SIGMAR1AOC3ALDH1A1KMT2A
SCHEMBL10582602 0.76 IDO1 (0.34) TAAR1SIGMAR1AOC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307106-B1 P- OR M-TERT BUTOXYPHENETHYL ALCOHOL AND PROCESS FOR PREPARING THE SAME HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1992-01-15 EP disclosed
EP-0307106-A1 P- or m-tert butoxyphenethyl alcohol and process for preparing the same HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1989-03-15 EP disclosed