SCHEMBL9621803

SCHEMBL9621803

O=[C]C1CCCCNC1=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 12/20 0.43
RAB9A P51151 2/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8986153 0.93
SCHEMBL9425878 0.74
SCHEMBL8613410 0.69 CCR2 (0.51) CCR2RAB9AHTTALDH1A1KDM4E
SCHEMBL5638813 0.69 CCR2 (0.51) CCR2RAB9AHTTALDH1A1KDM4E
SCHEMBL7083818 0.69 ALDH1A1 (0.39) CCR2RAB9AHTTALDH1A1KDM4E
SCHEMBL5639147 0.69 CCR2 (0.51) CCR2RAB9AHTTALDH1A1KDM4E
SCHEMBL6983208 0.68 CCR2 (0.46) CCR2RAB9AHTTALDH1A1KDM4E
SCHEMBL18794832 0.68
SCHEMBL3166096 0.68
SCHEMBL1091811 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202419-B1 LACTAM-BLOCK COPOLYMERS AlliedSignal Inc. (US) 1992-02-12 EP disclosed
EP-0129036-B1 POLYAMIDE-POLYOL BLOCK COPOLYMERS AND ANIONIC POLYMERIZATION PROCESS AlliedSignal Inc. (US) 1991-12-18 EP disclosed
US-4843127-A POLYCARBOXYLIC ACID WITH POLYETHER OR POLYSULFIDE ALLIED-SIGNAL INC. (US) 1989-06-27 US disclosed
EP-0129036-A2 Polyamide-polyol block copolymers and anionic polymerization process AlliedSignal Inc. (US) 1984-12-27 EP disclosed
US-4487920-A POLYLACTAM-POLYETHER COPOLYMERS; REATION INJECTION MOLDING; IMPACT STRENGTH ALLIED CORPORATION (US) 1984-12-11 US disclosed