Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178544 | 0.84 | SMN1; SMN2 (0.41) | NPC1RAB9ACA2ALDH1A1NPSR1 | |
| SCHEMBL9182116 | 0.84 | NPC1 (0.40) | NPC1RAB9ANPSR1TSHR | |
| SCHEMBL7525387 | 0.77 | NPC1 (0.37) | NPC1RAB9ATSHR | |
| SCHEMBL11729209 | 0.77 | RAB9A (0.47) | NPC1RAB9AALDH1A1NPSR1KDM4E | |
| SCHEMBL9460463 | 0.76 | NPC1 (0.38) | NPC1RAB9AALDH1A1 | |
| SCHEMBL9176034 | 0.75 | NPC1 (0.41) | NPC1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL6861439 | 0.74 | NPC1 (0.35) | NPC1RAB9A | |
| SCHEMBL3283327 | 0.74 | NPC1 (0.50) | NPC1RAB9AALDH1A1TSHRKDM4E | |
| SCHEMBL424271 | 0.74 | CA2 (0.52) | NPC1RAB9ACA2ALOX12ATM | |
| SCHEMBL29501855 | 0.74 | CA2 (0.52) | NPC1RAB9ACA2ALOX12ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257151-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| EP-0257151-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |