Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485462 | 0.83 | TSHR (0.36) | CTSSCTSKTSHR | |
| SCHEMBL473139 | 0.83 | TSHR (0.36) | CTSSCTSKTSHR | |
| SCHEMBL473223 | 0.83 | TSHR (0.36) | CTSSCTSKTSHR | |
| SCHEMBL19759004 | 0.82 | CYP2D6 (0.33) | CTSSCTSKAPLNRCYP2D6APP | |
| Hydrochloric Acid SCHEMBL28201424 | 0.81 | TSHR (0.35) | CTSSCTSKTSHR | |
| SCHEMBL30507610 | 0.79 | CA1 (0.39) | CTSSCTSKKMT2ACYP2D6APP | |
| SCHEMBL12139937 | 0.79 | CA1 (0.39) | CTSSCTSKKMT2ACYP2D6APP | |
| SCHEMBL2965180 | 0.77 | ALDH1A1 (0.40) | TSHRLMNA | |
| SCHEMBL29029716 | 0.76 | NOS1 (0.39) | CTSSCTSKTSHRLMNAKMT2A | |
| SCHEMBL29029714 | 0.76 | NOS1 (0.39) | CTSSCTSKTSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097045-A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1992-03-17 | — | — | US | disclosed |