Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544994 | 0.80 | — | — | |
| SCHEMBL3360225 | 0.80 | — | — | |
| SCHEMBL1783372 | 0.80 | — | — | |
| SCHEMBL8020521 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL4491106 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL3619295 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL3619291 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL27343912 | 0.77 | SOAT1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL27392590 | 0.77 | CYP3A4 (0.46) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL9621866 | 0.77 | CTSS (0.32) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715632-B | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109715632-A | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| EP-1238704-B1 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | DAICEL CHEM (JP) | 2015-01-21 | — | — | EP | disclosed |
| EP-1433527-B1 | CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS | DAICEL CHEM (JP) | 2013-11-06 | — | — | EP | disclosed |
| US-7759515-B2 | Catalyst comprising N-substituted cyclic imide compound and process for producing organic compounds using the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7741514-B2 | Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-22 | — | — | US | disclosed |
| US-7368615-B2 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| EP-1055654-B1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | DAICEL CHEM (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-7288649-B2 | Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-10-30 | — | — | US | disclosed |
| US-7183423-B1 | Process for the preparation of organic compounds with imide catalysts | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20060030716-A1 | Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst | ISHII YASUTAKA | 2006-02-09 | — | — | US | disclosed |
| US-20050020439-A1 | Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1459804-A1 | CATALYSTS COMPRISING CYCLIC ACYLUREA COMPOUNDS AND PROCESSES FOR PRODUCTION OF ORGANIC COMPOUNDS WITH THE SAME | Daicel Chemical Industries, Ltd. (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-1433527-A1 | CATALYSTS COMPRISED OF N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20040053778-A1 | Catalyst comprised of n-substituted cyclic imides and processes for preparing organic compounds with the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1338336-A1 | CATALYSTS COMPRISING N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-20030013603-A1 | Catalyst comprising n-substituted cylic imides and processes for preparing organic compounds with the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| US-20020128149-A1 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1238704-A2 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | Daicel Chemical Industries, Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-1055654-A1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128149-A1 | Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst | NOX4, POR, NOX1 | ALDH1A1 1339/4885LMNA 3854/4885HSD17B10 2127/4885 |
| US-20060030716-A1 | Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst | MOGAT2, HAT1, ACOX1 | ALDH1A1 261/4885LMNA 4250/4885HSD17B10 304/4885 |
| US-20050020439-A1 | Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same | MOGAT2, ACSS2, ACOX1 | ALDH1A1 258/4885LMNA 4215/4885HSD17B10 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.