Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 5/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621876 | 1.00 | CRHBP (0.52) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9621906 | 0.90 | CRHBP (0.43) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9621901 | 0.90 | CRHBP (0.43) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9621983 | 0.89 | CRHBP (0.59) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9621981 | 0.89 | CRHBP (0.59) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10866520 | 0.87 | CRHBP (0.49) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9739737 | 0.84 | CRHBP (0.48) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10926838 | 0.79 | CRHBP (0.47) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9622515 | 0.75 | SMN1; SMN2 (0.42) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9622519 | 0.75 | SMN1; SMN2 (0.42) | CRHBPCRHR2LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470430-A1 | Process for the preparation of oxyguanidins | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |