Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 4/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621906 | 1.00 | CRHBP (0.43) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9621874 | 0.90 | CRHBP (0.52) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9621876 | 0.90 | CRHBP (0.52) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9622515 | 0.83 | SMN1; SMN2 (0.42) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9622519 | 0.83 | SMN1; SMN2 (0.42) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9740218 | 0.81 | L3MBTL1 (0.44) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9621983 | 0.80 | CRHBP (0.59) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9621981 | 0.80 | CRHBP (0.59) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9738143 | 0.78 | L3MBTL1 (0.44) | CRHBPCRHR2L3MBTL1LMNAKMT2A | |
| SCHEMBL9738657 | 0.78 | CRHBP (0.39) | CRHBPCRHR2L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470430-A1 | Process for the preparation of oxyguanidins | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |