Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ACP3 | P15309 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431412 | 0.71 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8522922 | 0.70 | SLC6A4 (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL22558182 | 0.69 | SLC1A2 (0.67) | SMN1; SMN2LMNAKMT2ASLC1A2HTT | |
| SCHEMBL22558181 | 0.69 | SLC1A2 (0.67) | SMN1; SMN2LMNAKMT2ASLC1A2HTT | |
| SCHEMBL30495979 | 0.69 | SLC1A2 (0.67) | SMN1; SMN2LMNAKMT2ASLC1A2HTT | |
| SCHEMBL9461581 | 0.68 | LMNA (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27603655 | 0.67 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1LMNAKMT2ASLC1A2 | |
| N-Benzylmethylamine SCHEMBL29834172 | 0.67 | LMNA (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11347598 | 0.67 | SLC1A2 (0.50) | KMT2ASLC1A2 | |
| SCHEMBL18836847 | 0.67 | NPC1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136658-B1 | -1-BENZYL-AMINOALKYL-PYRROLIDINONES AND THEIR ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING THEM | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | claimed |
| EP-0136658-A2 | -1-Benzyl-aminoalkyl-pyrrolidinones and their addition salts, process for their preparation and pharmaceutical compounds containing them | BOEHRINGER INGELHEIM KG (DE) | 1985-04-10 | — | — | EP | claimed |
| JP-4261152-A | — | — | None | — | — | JP | disclosed |
| JP-H04261152-A | NOVEL 1-BENZYL-AMINOALKYL-PYRROLIDINONE COMPOUND AND ITS PRODUCTION | BOEHRINGER INGELHEIM KG | 1992-09-17 | — | — | JP | disclosed |
| EP-0266563-B1 | USE OF 1-BENZYL-AMINO-ALKYL-PYRROLIDINONES AS ANTIDEPRESSANTS | BOEHRINGER INGELHEIM KG (DE) | 1992-01-29 | — | — | EP | disclosed |
| EP-0266563-B1 | USE OF 1-BENZYL-AMINO-ALKYL-PYRROLIDINONES AS ANTIDEPRESSANTS | BOEHRINGER INGELHEIM KG (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4954516-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1990-09-04 | — | — | US | disclosed |
| US-4954516-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1990-09-04 | — | — | US | disclosed |
| US-4954516-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1990-09-04 | — | — | US | disclosed |
| US-4912129-A | Administering to humans | BOEHRINGER INGELHEIM GMBH (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4912129-A | Administering to humans | BOEHRINGER INGELHEIM GMBH (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0136658-B1 | -1-BENZYL-AMINOALKYL-PYRROLIDINONES AND THEIR ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING THEM | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | disclosed |
| US-4812453-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1989-03-14 | — | — | US | disclosed |
| US-4812453-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1989-03-14 | — | — | US | disclosed |
| US-4812453-A | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0266563-A2 | Use of 1-benzyl-amino-alkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266563-A2 | Use of 1-benzyl-amino-alkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266563-A2 | Use of 1-benzyl-amino-alkyl-pyrrolidinones as antidepressants | BOEHRINGER INGELHEIM KG (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0136658-A2 | -1-Benzyl-aminoalkyl-pyrrolidinones and their addition salts, process for their preparation and pharmaceutical compounds containing them | BOEHRINGER INGELHEIM KG (DE) | 1985-04-10 | — | — | EP | disclosed |
| EP-0136658-A2 | -1-Benzyl-aminoalkyl-pyrrolidinones and their addition salts, process for their preparation and pharmaceutical compounds containing them | BOEHRINGER INGELHEIM KG (DE) | 1985-04-10 | — | — | EP | disclosed |