Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076324 | 0.77 | KMT2A (0.46) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL9048459 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL9621922 | 0.70 | CHRM2 (0.39) | KMT2ASMN1; SMN2 | |
| SCHEMBL10524000 | 0.69 | POLB (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10524011 | 0.69 | POLB (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8773823 | 0.68 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL1101369 | 0.68 | MEN1 (0.59) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL7368104 | 0.68 | MEN1 (0.59) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL27878470 | 0.68 | ALDH1A1 (0.49) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL10316558 | 0.68 | SIGMAR1 (0.50) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955296-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-4988814-A | Antidepressants and/or anxiolytic agents | AMERICAN HOME PRODUCTS CORP. (US) | 1991-01-29 | — | — | US | disclosed |