Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622132 | 0.87 | KDM4E (0.51) | POLBMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10424447 | 0.84 | KDM4E (0.59) | MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL8707349 | 0.84 | ALDH1A1 (0.45) | SRD5A2POLBMEN1NPC1RAB9A | |
| SCHEMBL9502109 | 0.82 | SRD5A2 (0.72) | SRD5A2POLBMEN1NPC1RAB9A | |
| SCHEMBL8461109 | 0.80 | SRD5A2 (0.77) | SRD5A2POLBNR1H4MEN1NPC1 | |
| SCHEMBL9622665 | 0.79 | SRD5A2 (0.54) | SRD5A2NR1H4MEN1NPC1RAB9A | |
| SCHEMBL13465507 | 0.79 | SRD5A2 (0.68) | SRD5A2POLBMEN1NPC1RAB9A | |
| SCHEMBL11591905 | 0.79 | PTPN1 (0.50) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1406448 | 0.77 | CTSA (0.44) | POLBMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL10540302 | 0.75 | RARB (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |