Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707349 | 0.83 | ALDH1A1 (0.45) | SRD5A2SMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL9622132 | 0.81 | KDM4E (0.51) | NPC1RAB9AALDH1A1LMNAGAA | |
| SCHEMBL11591905 | 0.81 | PTPN1 (0.50) | SMN1; SMN2NPC1RAB9ATDP1GRIN2C | |
| SCHEMBL5712086 | 0.79 | SRD5A2 (0.73) | SRD5A2SIRT1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9622083 | 0.79 | SRD5A2 (0.54) | SRD5A2NPC1RAB9ANR1H4DHODH | |
| SCHEMBL10424447 | 0.78 | KDM4E (0.59) | NPC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23909564 | 0.77 | LCK (0.46) | SMN1; SMN2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL23909524 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2TDP1GRIN2CDHODHALDH1A1 | |
| SCHEMBL10543973 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9ARARBRARG | |
| SCHEMBL9622692 | 0.76 | S1PR1 (0.44) | SRD5A2SMN1; SMN2TDP1DHODHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |