Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449453 | 0.87 | MYC (0.50) | MYCGAATSHRHPGDEDNRA | |
| SCHEMBL8816538 | 0.79 | HTT (0.43) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10355854 | 0.74 | EDNRA (0.50) | TSHRALDH1A1EDNRAEDNRBHDAC4 | |
| SCHEMBL11527593 | 0.74 | EDNRA (0.50) | TSHRALDH1A1EDNRAEDNRBHDAC4 | |
| SCHEMBL20169172 | 0.73 | LMNA (0.44) | GAAALDH1A1EDNRAEDNRBHDAC4 | |
| SCHEMBL6023644 | 0.73 | HDAC4 (0.41) | GAATSHRALDH1A1EDNRAEDNRB | |
| SCHEMBL30838752 | 0.73 | HTR2B (0.46) | MYCTSHRALDH1A1HTR2BHTR7 | |
| SCHEMBL28618542 | 0.73 | HTR2B (0.46) | MYCTSHRALDH1A1HTR2BHTR7 | |
| SCHEMBL8817282 | 0.72 | HTT (0.55) | TSHRHPGDHDAC4TP53HTT | |
| SCHEMBL9449948 | 0.72 | HDAC3 (0.44) | MYCALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079260-A | Side effect reduction; fluorene derivatives | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| WO-1991018596-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | WEITZBERG MOSHE (US) | 1991-12-12 | — | — | WO | disclosed |