SCHEMBL30838752

SCHEMBL30838752

Cc1cccc2c1-c1c(C)cccc1C2O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 5/20 0.46
HTR7 P34969 2/20 0.46
ALDH1A1 P00352 1/20 0.42
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TRPA1 O75762 2/20 0.37
CD44 P16070 1/20 0.37
ATM Q13315 1/20 0.37
DRD2 P14416 2/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
MYC P01106 1/20 0.36
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36
HTR2C P28335 4/20 0.36
HTR2A P28223 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28618542 1.00 HTR2B (0.46) HTR2BHTR7ALDH1A1MAOAMAOB
SCHEMBL8750096 0.85 HTR2B (0.51) HTR2BHTR7ALDH1A1MAOAMAOB
SCHEMBL12836976 0.75 ALDH1A1 (0.42) HTR2BHTR7ALDH1A1MAOAMAOB
SCHEMBL9622343 0.75 ALDH1A1 (0.37) HTR2BALDH1A1CYP1A2CYP2A6TRPA1
SCHEMBL9622137 0.73 MYC (0.44) HTR2BHTR7ALDH1A1CA1CA2
SCHEMBL4021982 0.71 ACHE (0.57) ALDH1A1CYP1A2CYP2A6TRPA1CD44
SCHEMBL18826578 0.70 CA1 (0.38) HTR2BHTR7MAOAMAOBATM
SCHEMBL27776809 0.70 ALDH1A1 (0.37) HTR2BALDH1A1CYP1A2CYP2A6CD44
SCHEMBL18989345 0.70 HTR2B (0.51) HTR2BHTR7MAOAMAOBDRD2
SCHEMBL11358726 0.69 HTR2A (0.54) HTR2BALDH1A1CYP1A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264883-B Method for rapidly synthesizing phenanthridine compounds 中国科学技术大学 2024-02-23 CN disclosed